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Software for calculating IORT treatments with a LIAC HWL linac, based on precalculated Monte Carlo dose distributions in water.

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**Software for calculating IORT treatments with a LIAC HWL linac, based on precalculated Monte Carlo dose distributions in water.**

[![License: MIT](https://img.shields.io/badge/License-MIT-yellow.svg)](https://opensource.org/licenses/MIT)
![Python Version from PEP 621 TOML](https://img.shields.io/python/required-version-toml?tomlFilePath=https%3A%2F%2Fraw.githubusercontent.com%2Fradiofisica-hgugm%2Fkali_mc%2Fmain%2Fpyproject.toml)
[![Code Style: Black](https://img.shields.io/badge/code%20style-black-000000.svg)](https://github.com/radiofisica-hgugm/kali_mc/actions/workflows/pre-commit.yml)
[![Documentation Status](https://readthedocs.org/projects/kali-mc/badge/?version=latest)](https://kali-mc.readthedocs.io/en/latest/?badge=latest)
[![DOI](https://zenodo.org/badge/DOI/10.5281/zenodo.14009299.svg)](https://doi.org/10.5281/zenodo.14009299)

## Main Features:
- Visualize absorbed dose distributions of all combinations of applicators and energies
- Calculate monitor units (MU) with measured output factors at zmax
- Atmospheric pressure correction available
- Rescaling factors can be added for desired applicator/energy combinations
- Report generation in pdf
- Send data as RTPlan to Record and Verify software (only tested with MOSAIQ)
- Support for user customized data: output factors, R90 values and rescaling factors.

## Limitations:
- The software is intended for educational purposes
- The Monte Carlo model was fitted to the data acquired at Gregorio Marañón hospital, Madrid.
  Different linacs may show dosimetric differences.

## Documentation:
[https://kali-mc.readthedocs.io/](https://kali-mc.readthedocs.io/)

## How to cite:
If you use Kali MC in your work, please cite the article describing the software:

*Ayala R, García R, Ruiz G, Gómez S, Santos M, Álvarez A, García MJ, Soza Á, Udías JM, Ibáñez P. Kali MC: an open-source toolkit for intraoperative electron radiation therapy treatment planning. Biomed Phys Eng Express. 2026;12(3):037001. https://doi.org/10.1088/2057-1976/ae5f9d*

## Additional data:
Monte Carlo Phase Space Files (PSFs) that give rise to the displayed absorbed dose distributions are available here:
 [![DOI](https://zenodo.org/badge/DOI/10.5281/zenodo.14029134.svg)](https://doi.org/10.5281/zenodo.14029134)

More information about the Monte Carlo modelling of the Liac HWL mobile accelerator can be found in:

*Ayala R, Soza Á, García MJ, García R, Udías JM, Ibáñez P. Development and validation of a Monte Carlo model of a mobile accelerator for intraoperative radiation therapy. Med Phys. 2025; 52:e18040. https://doi.org/10.1002/mp.18040*

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