LOICA

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Logical Operators for Integrated Cell Algorithms

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# LOICA

Welcome to the LOICA (Logical Operators for Integrated Cell Algorithms) repository, our Python package for designing, modeling and characterizing genetic networks.

![PyPI](https://img.shields.io/pypi/v/loica)
[![Documentation Status](https://readthedocs.org/projects/loica/badge/?version=latest)](https://loica.readthedocs.io/en/latest/)
![PyPI - Python Version](https://img.shields.io/pypi/pyversions/loica)
![PyPI - License](https://img.shields.io/pypi/l/loica)

As you may have noticed, our logo features a beautiful bird—loica _[(Leistes loyca)](https://en.wikipedia.org/wiki/Long-tailed_meadowlark)_; a bird native to Chile known for its particular red chest and legendary kindness, with which we share name[.](https://youtu.be/qDL3zhB8-MM)

## Reference and citation

LOICA is an academic open source software for science, if you want to reference or cite it please use the following:

DOI https://doi.org/10.1021/acssynbio.1c00603

Get the BibTeX in [Google Scholar](https://scholar.google.com/scholar?hl=es&as_sdt=0%2C5&q=LOICA%3A+Integrating+Models+with+Data+for+Genetic+Network+Design+Automation&btnG=)

## Installation

Installing LOICA is way easier than pronuncing it!

Do:

`pip install loica`

For more details please refer to our [Wiki](https://github.com/RudgeLab/LOICA/wiki) for installation instructions and developer guides.

## LOICA allows you to:

- Compile Code into DNA fragments that execute Cell Algorithms
- Easy programation of genetic network models
- Generation of synthetic data
- Communicate with Flapjack
- Use and output SBOL files
- Use all sorts of cellular computation
- Easy, fluid and customisable DNA design

## Documentation

Please visit our documentation with API reference at Read the Docs: [loica.readthedocs.io](https://loica.readthedocs.io/en/latest/).

## Tutorials

Now that you have LOICA installed you can familiarize yourself with the tool using the [Jupyter notebook tutorials](https://github.com/RudgeLab/LOICA/tree/master/notebooks) designed for this purpose.

Run LOICA on the web without any installation! [LOICA Colab Notebook](https://drive.google.com/file/d/1xxxMS5amaTGY2Z09i5h03zMr2J2zGiwg/view?usp=sharing)

You can use and modify this code by saving a copy in Drive.

LOICA

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