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mr-base-methods-paper
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mr-base-methods-paper
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# Analysis for MR Base methods paper ## Run main MR analysis Perform analysis of LDL, trigs, Lp(a) on all best outcomes ``` cd scripts Rscript run_mr.R ``` This saves a file in `results/lpa_ldl_trigs.RData` which contains the instruments published by Willer et al, and those variants extracted from a large set of disease and risk factor GWASs. ## Generate graphs LDL-CHD plots ``` Rscript ldl-chd.R ``` Sensitivity analyses for all exposure - outcome pairs with p < 0.05: ``` Rscript figure_sensitivity_boxes.R ``` Volcano plots: ``` Rscript figure_volcano_plots.R ``` ## Create tables ``` Rscript tables.R ``` ## PheWAS scripts ``` Rscript PheWAS.R ```
