transcriptional-map-nk

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transcriptional-map-nk

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We describe a transcriptional reference map of human natural killer (NK) cells based on analysis of scRNA-seq data from both blood and tissue. We also analyze data from various solid tumors and map these onto this reference.

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# Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping
We describe a transcriptional reference map of human natural killer (NK) cells based on analysis of scRNA-seq data from both blood and tissue. We also analyze data from various solid tumors and map these onto this reference.

### Data
The gene expression data generated for this paper is available at NCBI GEO with accession number GSE245690 and raw sequencing data is available at EGA with accession number EGAS50000000014. The details about the publicly available data included in the analysis are available in Supplemental tables S1, S2 and S3. Processed data and models have also been made available on Zenodo (https://doi.org/10.5281/zenodo.10139343) and as an online resource at http://nk-scrna.malmberglab.com/.

### Citation

Netskar, H., Pfefferle, A., Goodridge, J.P. et al. Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping. Nat Immunol (2024). https://doi.org/10.1038/s41590-024-01884-z

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